By John S. Bradley MD, John D. Nelson MD Emeritus, Dr. David W Kimberlin MD FAAP, Dr. John A.D. Leake MD MPH, Dr. Paul E Palumbo MD, Dr. Jason Sauberan PharmD, Dr. William J Steinbach
New twentieth Edition! This bestselling and favourite source on pediatric antimicrobial remedy presents immediate entry to trustworthy, up to the moment suggestions for remedy of all infectious ailments in little ones.
For every one illness, the authors offer a remark to assist healthiness care services decide upon the simplest of all antimicrobial choices. Drug descriptions disguise all antimicrobial brokers to be had at the present time and contain entire information regarding dosing regimens. based on starting to be matters approximately overuse of antibiotics, this system comprises directions on while to not prescribe antimicrobials.
Practical, evidence-based ideas from the specialists in antimicrobial treatment:
Developed via uncommon editorial board
Designed if you look after teenagers and are confronted with judgements each day
Includes therapy of parasitic infections and tropical medicine.
Updated tests concerning the energy of the advice and the point of proof for therapy strategies for significant infections
Anti-infective drug directory, whole with formulations and dosages
Antibiotic treatment for overweight children
Antimicrobial prophylaxis/prevention of symptomatic infection
Maximal grownup dosages and better dosages of a few antimicrobials normal in children
Read or Download 2014 Nelson's Pediatric Antimicrobial Therapy PDF
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Extra info for 2014 Nelson's Pediatric Antimicrobial Therapy
For newborns whose mothers received NO antenatal intervention, add 3 doses of NVP in the first week of life (1st dose at 0-48 h; 2nd dose 48 h later; 3rd dose 96 h after 2nd dose) to the 6 wk of ZDV treatment. 5–2 kg: 8 mg/dose PO; Birth weight >2 kg: 12 mg/dose PO. 51 The preventive ZDV doses listed above for neonates are also treatment doses for infants with diagnosed HIV infection. Note that antiretroviral treatment doses for neonates are established only for ZDV and 3TC. Treatment of HIV-infected neonates should be considered only with expert consultation.
Ampicillin IV, IM AND gentamicin IV, IM for 7–10 days (AIII) Azithromycin PO, IV q24h for 5 days OR erythromycin ethylsuccinate PO for 14 days (AII) Clindamycin PO, IV for 10 days (organisms are resistant to macrolides) Azithromycin 10 mg/kg PO, IV q24h for 5 days OR erythromycin ethylsuccinate PO for 14 days (AII) –– Empiric therapy of the neonate with early onset of pulmonary infiltrates (within the first 48–72 h of life) –– Aspiration pneumonia67 –– Chlamydia trachomatis68 –– Mycoplasma hominis69,70 –– Pertussis71 Association of erythromycin and pyloric stenosis in young infants; may also occur with azithromycin Alternatives for >1 mo of age, clarithromycin for 7 days, and for >2 mo of age, TMP/SMX for 14 days Pathogenic role in pneumonia not well defined and clinical efficacy unknown; no association with bronchopulmonary dysplasia (BIII).
CT scan to confirm cure (BIII). 6 Cellulitis, periorbital57 (preseptal infection) Therapy (evidence grade) Cefotaxime 150 mg/kg/day div q8h or ceftriaxone 50 mg/kg/day q24h; ADD (for S aureus, including CA-MRSA): clindamycin 30 mg/kg/day IV div q8h OR vancomycin 40 mg/kg/day IV q8h (AIII). If MSSA isolated, use: oxacillin/nafcillin IV OR cefazolin IV Cellulitis, orbital53–55 (usually secondary to sinus infection; caused by respiratory tract flora and S aureus, including CA-MRSA) C. EYE INFECTIONS Antimicrobial Therapy According to Clinical Syndromes Clinical Diagnosis 44 — Chapter 6.