By Martin J. Pfeiffer, Martin Stehling, Anna Jauch (auth.), Hossein Baharvand, Nasser Aghdami (eds.)
Advances in Stem telephone Research discusses contemporary advances in stem mobilephone technological know-how, together with healing purposes. This quantity covers such issues as biomanufacturing iPS cells for healing functions, innovations for controlling stem mobilephone destiny judgements, in addition to present simple examine in such components as germ line stem cells, genomics and proteomics in stem phone learn. it's a important publication for biology and medical scientists, specifically younger investigators and stem mobile biology scholars who're newly coming into the area of stem cells study. The editors wish that the hot wisdom and learn defined during this e-book might help give a contribution to new remedies for a large choice of ailments that almost immediately afflict humanity.
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Depending on the particular cell type generated and its specific application, functional benchmarks must also be met. For example, cardiomyocytes must be able to electromechanically integrate with native heart tissue and islet cells must secrete insulin in a glucose-dependent manner. Product safety is of utmost concern in cell-based therapeutics. Culture contamination by bacteria, fungi, viruses, and endotoxins must be monitored by genetic and/or chemical testing. hPSCs are prone to acquiring chromosomal abnormalities, typically gains of chromosome arms or full chromosomes, that increase expansion rates and affect differentiation potential .
Cell density must be increased by orders of magnitude compared to lab scale culture. This is typically achieved by culture in suspension or on suspended microparticles. However, hPSCs are prone to aggregation in suspension and are sensitive to shear stresses. Cell aggregates are heterogeneous in size and may severely limit diffusion of nutrients, growth factors, metabolic byproducts, and dissolved gases within the aggregate, which may in turn affect expansion potential, lead to spontaneous differentiation, or cause or acquisition of abnormal karyotypes.
Nat Biotechnol 27(3): 281–287 19. Jung SH, Shin SH, Yim SH, Choi HS, Lee SH, Chung YJ (2009) Integrated analysis of copy number alteration and RNA expression profiles of cancer using a high-resolution wholegenome oligonucleotide array. Exp Mol Med 41(7):462–470 20. Ganguly A, Nichols KE, Grant G, Rappaport E, Shields C (2009) Molecular karyotype of sporadic unilateral retinoblastoma tumors. Retina 29(7):1002–1012. 0b013 e3181a0be05 21. 2 * p12 in osteosarcoma. Cancer Genet Cytogenet 153(1):77–80 22.