Download Biofunctional Textiles And the Skin (Current Problems in by U.-C. Hipler, P. Elsner, P. Itin, G.B.E. Jemec PDF

By U.-C. Hipler, P. Elsner, P. Itin, G.B.E. Jemec

In recent times, the improvement of recent applied sciences has authorized the creation of 'functional' or 'smart' textiles. those materials are in a position to sensing adjustments in environmental stipulations or physique services and are competently responding to them. they may be able to take up elements from the outside or to unencumber healing or beauty compounds. for example, they are often utilized in undies with an built-in cardio-on-line process or as textiles with service molecules. the point of interest of curiosity in biofunctional textiles lies at present at the use of textiles assisting treatment and prevention in dermatology. This quantity collects information regarding new developments within the interplay among textiles and the outside, relatively the improvement of antimicrobial-finished textiles. It offers a range of papers in order to give a contribution to additional consolidate the discussion among dermatologists, allergologists, biomaterial scientists and fabric engineers.

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Additional resources for Biofunctional Textiles And the Skin (Current Problems in Dermatology)

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The bacteria of the resident flora of the normal human skin live as microcolonies [7] on and between the layers of the stratum corneum [8] and in the follicles of the sebaceous glands [9]. In the uppermost layer of the stratum corneum, Corynebacterium spp. and sometimes microorganisms of the transient skin flora are present. In the infundibulum of the sebaceous glands, there is a topographic distribution of Propionibacterium spp. from the deepest part of the infrainfundibulum up to the entrance of the acroinfundibulum and of coagulase-negative staphylococci from the middle part of the infundibulum to its entrance.

At concentrations of up to 50 mgиlϪ1, silver sulphadiazine is claimed to be effective against up to 95% of bacteria commonly found in skin wounds. The low toxicity and antibacterial efficacy of sulphadiazine have been developed in a number of wound dressings using different vehicles and polymers (polyethylene glycol ϩ poly-2-hydroxyethyl methacrylate, liposomes, poly-L-leucine and cadaver skin). 75% silver sulphadiazine (Urgotul® SSD, Urgo-Parema Medical) is currently available and efficacious in treating acute and chronic wounds infected with a wide range of infections including MRSA [20].

Occasionally, other antibiotics including gentamycin, chlorhexidine gluconate or rifampicin have been included to complement the action of silver. Silver sulphadiazine and chlorhexidine gluconate act in a form of ‘synergy’ whereby the chlorhexidine gluconate serves to denature the bacterial cell membrane allowing improved ingression of silver ions. The copper ion exhibits a similar effect in medical catheters. Copper:silver filters are widely used in the purification of hospital water systems against Legionella sp.

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